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Automation Scientist

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Posted : Monday, December 18, 2023 02:55 AM

About Karius Karius is a venture-backed life science startup that is transforming the way pathogens and other microbes are observed throughout the body.
By unlocking the information present in microbial cell-free DNA, we're helping doctors quickly solve their most challenging cases, providing industry partners with access to 1000’s of biomarkers to accelerate clinical trials, discovering new microbes, and reducing patient suffering worldwide.
Why Should You Join? Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning.
The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions.
The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients.
Our test is the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission.
You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale.
Position Summary As an Automation Scientist I, you will work alongside other scientific leaders in NGS-based infectious disease diagnostics providing meaningful contributions to making an impact in the lives of patients while contributing to the company’s growth and development.
You will be responsible for working with our R&D team for developing, testing, and optimizing new automated methods.
In that process you may also be required to do data analysis to analyze the results of your automated methods.
You will also be responsible for the release of new or updated methods to and training of the Production staff on these methods.
Another function of the role is maintaining and supporting process excellence for a state-of-the art NGS infectious disease diagnostic assay in our CLIA production lab which includes the support of our commercial operations by maintaining and troubleshooting CLIA-validated automation systems, expanding the commercial lab capacity by validating new robotic platforms and increasing the throughput of the existing ones.
The ideal candidate should have experience working in a laboratory environment, have experience in programming liquid handlers - Hamilton preferred, and be willing to be challenged and learn new skills.
Reports to: Manager, Automation Location: Redwood City, CA Primary Responsibilities • Upgrade instruments and software when applicable.
• Programming, developing, optimizing, and validating new automated methods.
• Design and optimize automated workflows for high-throughput processing of clinical samples, library prep and NGS.
• Scope out project needs for new automated methods.
• Work cross-functionally to ensure successful project execution and meeting deliverables on time.
• Interface with lab automation suppliers for service visits, installations, and other needs.
• Conduct manufacturing and experimental processes according to established SOPs.
• Document and develop new SOPs for new processes and validation reports for automated processes and contribute to regulatory submissions as needed.
• Support of automated CLIA diagnostic processes.
• Train lab personnel on operation, maintenance and troubleshooting of automated systems and provide technical support as needed.
• Mentor junior associates.
• Work comfortably in a fast-paced, collaborative, startup environment.
• May be required to perform other duties as assigned.
• Staying updated on advancements in automation technologies, genomics, infectious disease diagnostics to propose and implement innovative solutions.
• Troubleshoot technical issues related to automated systems, perform routine maintenance, and ensure compliance with regulatory standards and quality control measures.
What’s Fun About the Job? Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics.
With that, comes a wave of new and incredible challenges and opportunities.
To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice.
You will get to see how much your work really matters.
Travel: No travel required.
Physical Requirements Subject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels.
Position Requirements • Bachelor's degree in Biology, Molecular Biology, or related field (advanced degree preferred).
• Minimum of 3+ years industry experience • Minimum of 3 years of Hamilton programming and troubleshooting experience.
• Proven record of critical thinking, attention to detail, good presentation skills, good communication skills, and thorough record-keeping.
• Experienced with equipment and processes used in NGS diagnostics (PCR thermocyclers, extraction, library generation, etc.
) desirable.
• Experience with Microsoft Office Excel and Word.
Also, experience with advanced analytical tools like (JMP, R, and Matlab) is desirable.
Preferred Requirements • Experience with automating molecular biology processes, e.
g.
DNA/RNA purification, and NGS library generation.
• Experience with NGS library processes and data processing.
• Hamilton software training.
Personal Qualifications • Ability to work independently and collaboratively with team members.
• Highly goal-driven and have demonstrated the ability to effectively prioritize and focus on time-sensitive objectives.
• Strong problem-solving and troubleshooting skills.
• Excellent teamwork and motivation skills are essential.
• Excellent organizational, record-keeping and communication (verbal and written) skills.
• Strong work ethic to generate high quality work under tight deadlines.
At Karius, we value a diverse and inclusive workplace and provide equal employment opportunity for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company.
All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws.
If you are unable to submit your application due to a disability, please contact us at recruiting@kariusdx.
com and we will accommodate qualified individuals with disabilities.
$114,655 - $133,764 a year

• Phone : NA

• Location : Redwood City, CA

• Post ID: 9136711251


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